Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flurtamone SCHEMBL54435 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53MAPTNOTUMMAPK14 | |
| Flurtamone SCHEMBL29352097 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53MAPTNOTUMMAPK14 | |
| Flurtamone SCHEMBL29538320 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53MAPTNOTUMMAPK14 | |
| SCHEMBL10712878 | 0.91 | KCNN4 (0.37) | TP53MAPTNOTUMMAPK14BRD4 | |
| SCHEMBL10849707 | 0.90 | TACR1 (0.36) | SMN1; SMN2MAPTCYP2C19CNR2 | |
| SCHEMBL10827602 | 0.90 | NPC1 (0.43) | NOTUMMAPK14CYP2C19BRD4 | |
| SCHEMBL10711889 | 0.87 | PTGES (0.35) | SMN1; SMN2TP53MAPTNOTUMMAPK14 | |
| SCHEMBL10827321 | 0.87 | CYP1A2 (0.40) | MAPTCYP2C19 | |
| SCHEMBL7179889 | 0.86 | KIF11 (0.39) | TP53MAPT | |
| SCHEMBL10826984 | 0.86 | NOTUM (0.36) | NOTUMMAPK14BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |