Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834670 | 0.97 | ALDH1A1 (0.59) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL28745643 | 0.85 | NPC1 (0.69) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL557753 | 0.84 | NPC1 (0.73) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL10518453 | 0.83 | NPC1 (0.54) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL4117707 | 0.83 | NPC1 (0.77) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3878827 | 0.81 | NPC1 (0.55) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL899098 | 0.81 | NPC1 (0.59) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL28025287 | 0.81 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL10517136 | 0.81 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL28025164 | 0.81 | NPC1 (0.51) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |