Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973924 | 0.88 | ALDH1A1 (0.69) | ALDH1A1HPGDMAPTEGFRSMN1; SMN2 | |
| SCHEMBL3102333 | 0.86 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTEGFRSMN1; SMN2 | |
| SCHEMBL29859324 | 0.82 | TARBP2 (0.55) | ALDH1A1HPGDMAPTEGFRSMN1; SMN2 | |
| SCHEMBL28025699 | 0.82 | ALDH1A1 (0.79) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL28139604 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8536799 | 0.81 | NPC1 (0.58) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL10518453 | 0.81 | NPC1 (0.54) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL4117707 | 0.81 | NPC1 (0.77) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9834670 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTSMN1; SMN2KDM4E | |
| SCHEMBL3928153 | 0.80 | ESR1 (0.60) | ALDH1A1HPGDMAPTEGFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334477-A2 | Novel photoactive compounds, processes for their production and intermediates therefor | MTM RESEARCH CHEMICALS LIMITED (GB) | 1989-09-27 | — | — | EP | disclosed |