Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934457 | 0.79 | CYP2A6 (0.47) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL1232330 | 0.77 | MEN1 (0.39) | MAOBMAOACYP2A6MEN1TTR | |
| SCHEMBL4773225 | 0.76 | MEN1 (0.43) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL7505085 | 0.76 | CYP2A6 (0.32) | MAOBCYP2A6MEN1TTRALB | |
| SCHEMBL27528549 | 0.76 | LOXL2 (0.47) | MAOBMAOACYP2A6MEN1TTR | |
| SCHEMBL500133 | 0.76 | MEN1 (0.42) | MAOBMAOAMEN1TTRALB | |
| SCHEMBL4774237 | 0.75 | ALDH1A1 (0.37) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL27455430 | 0.74 | GSK3B (0.39) | MAOBMAOACYP2A6MEN1TTR | |
| SCHEMBL4767252 | 0.74 | TSHR (0.42) | CYP2A6MEN1TTRALBKMT2A | |
| SCHEMBL534995 | 0.74 | ALDH1A1 (0.41) | CYP2A6MEN1TTRALBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |