Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143951 | 0.81 | HSD11B1 (0.50) | HSD11B1GABRR1GABRR2SLC1A2 | |
| SCHEMBL28758390 | 0.81 | GRM2 (0.39) | HSD11B1GABRR1GABRR2POLBTDP1 | |
| SCHEMBL8537084 | 0.79 | HSD11B1 (0.48) | HSD11B1GABRR1GABRR2SLC1A2 | |
| SCHEMBL3139345 | 0.74 | HSD11B1 (0.35) | HSD11B1GABRR1GABRR2 | |
| SCHEMBL11048511 | 0.72 | GRM2 (0.37) | HSD11B1GABRR1GABRR2POLBSLC1A2 | |
| SCHEMBL8628131 | 0.72 | GABRR1 (0.50) | GABRR1GABRR2POLBTDP1SLC1A2 | |
| SCHEMBL2697233 | 0.72 | GABRR1 (0.50) | GABRR1GABRR2POLBTDP1SLC1A2 | |
| SCHEMBL9782991 | 0.72 | GABRR1 (0.50) | GABRR1GABRR2POLBTDP1SLC1A2 | |
| SCHEMBL13084744 | 0.72 | GABRR1 (0.50) | GABRR1GABRR2POLBTDP1SLC1A2 | |
| SCHEMBL22039 | 0.72 | GABRR1 (0.50) | GABRR1GABRR2POLBTDP1SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731405-A | POLYIMIDE COPOLYMER MADE FROM DIARYL KETONE TETRACARBOXYLIC DIANHYDRIDE, HYDROPHOBIC DIAMINE, AND ALICYCLIC TETRACARBOXYLIC ANHYDRIDE REACTANTS | ALLIANT TECHSYSTEMS INC. (US) | 1998-03-24 | — | — | US | claimed |
| WO-2020208884-A1 | FILM-FORMING COMPOSITION, CURED FILM, AND RETARDATION FILM | JSR株式会社 | 2020-10-15 | — | — | WO | disclosed |