Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.37 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143951 | 0.98 | HSD11B1 (0.50) | HSD11B1SLC6A12SLC6A11SLC6A13MEN1 | |
| SCHEMBL3139345 | 0.82 | HSD11B1 (0.35) | HSD11B1GABRR1GABRR2 | |
| SCHEMBL28758390 | 0.80 | GRM2 (0.39) | HSD11B1ALDH1A1LMNAGRM5GABRR1 | |
| SCHEMBL8537083 | 0.79 | HSD11B1 (0.36) | HSD11B1SLC1A2GABRR1GABRR2 | |
| SCHEMBL268091 | 0.78 | GABRR1 (0.48) | MEN1KMT2ASLC1A2TSHRTHPO | |
| SCHEMBL3139342 | 0.76 | HSD11B1 (0.32) | HSD11B1MEN1KMT2ASLC1A2MAPK1 | |
| SCHEMBL11048511 | 0.76 | GRM2 (0.37) | HSD11B1MEN1KMT2ASLC1A2MAPK1 | |
| SCHEMBL2697233 | 0.75 | GABRR1 (0.50) | MEN1KMT2ASLC1A2TSHRTHPO | |
| SCHEMBL13084744 | 0.75 | GABRR1 (0.50) | MEN1KMT2ASLC1A2TSHRTHPO | |
| SCHEMBL8628131 | 0.75 | GABRR1 (0.50) | MEN1KMT2ASLC1A2TSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731405-A | POLYIMIDE COPOLYMER MADE FROM DIARYL KETONE TETRACARBOXYLIC DIANHYDRIDE, HYDROPHOBIC DIAMINE, AND ALICYCLIC TETRACARBOXYLIC ANHYDRIDE REACTANTS | ALLIANT TECHSYSTEMS INC. (US) | 1998-03-24 | — | — | US | claimed |