Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658680 | 0.87 | KMT2A (0.74) | KMT2ANPC1MEN1L3MBTL1POLB | |
| SCHEMBL11920085 | 0.85 | KMT2A (0.44) | KMT2AMEN1L3MBTL1HTTMAPT | |
| SCHEMBL8535189 | 0.83 | KMT2A (0.68) | KMT2ANPC1MEN1L3MBTL1POLB | |
| SCHEMBL29041154 | 0.77 | KMT2A (1.00) | KMT2ANPC1MEN1L3MBTL1POLB | |
| SCHEMBL6509897 | 0.76 | KMT2A (0.72) | KMT2ANPC1MEN1L3MBTL1POLB | |
| SCHEMBL9751251 | 0.74 | KMT2A (0.70) | KMT2ANPC1MEN1L3MBTL1POLB | |
| SCHEMBL11220212 | 0.74 | KMT2A (0.70) | KMT2ANPC1MEN1L3MBTL1POLB | |
| Benzene SCHEMBL28216395 | 0.74 | KMT2A (0.56) | KMT2ANPC1MEN1L3MBTL1POLB | |
| SCHEMBL54072 | 0.74 | KMT2A (0.56) | KMT2ANPC1MEN1L3MBTL1POLB | |
| SCHEMBL2070001 | 0.74 | KMT2A (0.67) | KMT2ANPC1MEN1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |