Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESRRB | O95718 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658680 | 0.91 | KMT2A (0.74) | KMT2AMEN1NPC1L3MBTL1POLB | |
| SCHEMBL1156528 | 0.85 | KMT2A (0.69) | KMT2AMEN1NPC1L3MBTL1POLB | |
| SCHEMBL10645702 | 0.84 | TSHR (0.62) | KMT2AMEN1NPC1L3MBTL1POLB | |
| SCHEMBL375694 | 0.83 | ALDH1A1 (0.53) | KMT2AMEN1NPC1L3MBTL1POLB | |
| SCHEMBL8537199 | 0.83 | KMT2A (0.62) | KMT2AMEN1NPC1L3MBTL1POLB | |
| SCHEMBL375926 | 0.82 | ADRB2 (0.47) | KMT2AMEN1NPC1POLBHTT | |
| SCHEMBL5313367 | 0.81 | HAO1 (0.46) | KMT2AMEN1NPC1L3MBTL1HTT | |
| SCHEMBL29041154 | 0.81 | KMT2A (1.00) | KMT2AMEN1NPC1L3MBTL1POLB | |
| SCHEMBL13082074 | 0.80 | KMT2A (0.50) | KMT2AMEN1NPC1L3MBTL1POLB | |
| SCHEMBL5315001 | 0.80 | GSR (0.46) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |