Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.67 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264084 | 0.90 | HTR1A (0.62) | HTR1A | |
| SCHEMBL8544143 | 0.87 | HTR1A (0.73) | HTR1A | |
| SCHEMBL7530336 | 0.83 | HTR1A (0.73) | HTR1ADRD2HTR2A | |
| SCHEMBL4416131 | 0.83 | HTR1A (0.79) | HTR1A | |
| SCHEMBL9698246 | 0.83 | SLC6A4 (0.73) | HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL27447154 | 0.83 | HTR1A (0.71) | HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL4426960 | 0.82 | HTR1A (0.77) | HTR1A | |
| SCHEMBL9699011 | 0.82 | HTR6 (0.71) | HTR1ADRD2HTR2A | |
| SCHEMBL7961173 | 0.82 | HTR1A (0.70) | HTR1ADRD2HTR2A | |
| SCHEMBL5200827 | 0.81 | HTR1A (0.59) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496222-B1 | Indole derivatives | MERCK PATENT GMBH (DE) | 1998-09-09 | — | — | EP | disclosed |
| EP-0496222-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |