Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542579 | 0.82 | CA1 (0.39) | L3MBTL1CA1CA2CA4MEN1 | |
| SCHEMBL8542600 | 0.80 | ERCC5 (0.41) | CA1CA2CA4MEN1KMT2A | |
| SCHEMBL8539554 | 0.79 | CA1 (0.38) | L3MBTL1CA1CA2CA4MEN1 | |
| SCHEMBL8538198 | 0.78 | CA1 (0.38) | L3MBTL1CA1CA2CA4MEN1 | |
| SCHEMBL8543794 | 0.77 | CA1 (0.35) | CA1CA2CA4MEN1KMT2A | |
| SCHEMBL8538221 | 0.77 | CA1 (0.35) | CA1CA2CA4MEN1KMT2A | |
| SCHEMBL8544139 | 0.77 | KAT6A (0.38) | ALDH1A1MAPTSMN1; SMN2PARP1PARP15 | |
| SCHEMBL6777725 | 0.76 | RAB9A (0.50) | L3MBTL1CA1CA2MEN1KMT2A | |
| SCHEMBL8538572 | 0.76 | KMT2A (0.36) | CA1CA2CA4MEN1KMT2A | |
| SCHEMBL8542659 | 0.75 | CA1 (0.38) | CA1CA2CA4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |