Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 5/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542422 | 0.89 | PARP1 (0.36) | CA1CA2CA4PARP1PARP10 | |
| SCHEMBL8538564 | 0.89 | PARP1 (0.40) | CA1CA2CA4PARP1PARP10 | |
| SCHEMBL8536787 | 0.89 | PARP1 (0.40) | PARP1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8538094 | 0.89 | CES2 (0.42) | CA1CA2CA4PARP1MEN1 | |
| SCHEMBL8538385 | 0.88 | KCNK3 (0.43) | PARP1PARP10PARP15MEN1KMT2A | |
| SCHEMBL8538807 | 0.87 | KCNK3 (0.42) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL8542364 | 0.87 | CES2 (0.47) | PARP1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8542528 | 0.87 | SMN1; SMN2 (0.34) | CA1CA2CA4PARP1PARP10 | |
| SCHEMBL8544139 | 0.86 | KAT6A (0.38) | PARP1PARP10PARP15MAPTALDH1A1 | |
| SCHEMBL8536780 | 0.86 | MEN1 (0.39) | MEN1KMT2AMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |