Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27183074 | 0.85 | SRD5A2 (0.66) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL10903201 | 0.83 | MAPK1 (0.62) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL11059943 | 0.83 | LMNA (0.67) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL8537297 | 0.83 | MAPT (0.58) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL28723025 | 0.83 | CTSD (0.58) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL27853418 | 0.82 | POLB (0.77) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL11657714 | 0.81 | CES1 (0.57) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL11301789 | 0.81 | MAPK1 (0.60) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL30435123 | 0.81 | MAPK1 (0.60) | ALDH1A1MAPK1POLBCES1CES2 | |
| SCHEMBL27600575 | 0.81 | POLB (0.74) | ALDH1A1MAPK1POLBCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721233-A | Derivatives of 2,3-dihydro benzofuranols | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-24 | — | — | US | disclosed |