Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537345 | 1.00 | ESRRG (0.36) | ESRRGALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL7607103 | 0.89 | ESRRG (0.39) | ESRRGLMNASMN1; SMN2MAPTESRRB | |
| SCHEMBL7607097 | 0.89 | ESRRG (0.39) | ESRRGLMNASMN1; SMN2MAPTESRRB | |
| SCHEMBL7605705 | 0.78 | ALDH1A1 (0.46) | ESRRGALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL7605707 | 0.78 | ALDH1A1 (0.46) | ESRRGALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL7607896 | 0.78 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2MAPTKDM4ETDP1 | |
| SCHEMBL7607903 | 0.78 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2MAPTKDM4ETDP1 | |
| SCHEMBL5186509 | 0.73 | SMN1; SMN2 (0.43) | ESRRGALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL5494077 | 0.73 | SMN1; SMN2 (0.43) | ESRRGALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL5186521 | 0.73 | SMN1; SMN2 (0.43) | ESRRGALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887335-A1 | Precursor compounds | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-30 | — | — | EP | disclosed |