Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.68 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.68 |
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537923 | 0.95 | TOP2A (0.67) | TOP2ATOP2BNISCHGAATSHR | |
| SCHEMBL8536721 | 0.89 | NISCH (0.75) | TOP2ATOP2BNISCHALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8537245 | 0.86 | NISCH (0.71) | TOP2ATOP2BNISCHALDH1A1CYP1A2 | |
| SCHEMBL549191 | 0.81 | TOP2A (1.00) | TOP2ATOP2BNISCHGAATSHR | |
| Hydrochloric Acid SCHEMBL7734128 | 0.80 | TOP2A (1.00) | TOP2ATOP2BNISCHGAATSHR | |
| SCHEMBL6751839 | 0.78 | TOP2A (0.66) | TOP2ATOP2BNISCHGAATSHR | |
| SCHEMBL13327264 | 0.76 | NISCH (0.81) | TOP2ATOP2BNISCHGAATSHR | |
| SCHEMBL5441899 | 0.76 | NISCH (0.59) | TOP2ATOP2BNISCHGAATSHR | |
| SCHEMBL7724230 | 0.76 | TOP2A (1.00) | TOP2ATOP2BNISCHGAATSHR | |
| SCHEMBL5333970 | 0.75 | TOP2A (0.57) | TOP2ATOP2BNISCHGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | claimed |
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | disclosed |
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | disclosed |