Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.75 |
| ▸ | TOP2A | P11388 | 5/20 | 0.65 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8537245 | 0.97 | NISCH (0.71) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| SCHEMBL8537923 | 0.90 | TOP2A (0.67) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| SCHEMBL8537360 | 0.89 | TOP2A (0.68) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7748644 | 0.81 | NISCH (0.61) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| SCHEMBL5476725 | 0.80 | NISCH (0.79) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| SCHEMBL549282 | 0.79 | TOP2A (1.00) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| SCHEMBL8477719 | 0.76 | NISCH (0.55) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7734250 | 0.76 | TOP2A (0.96) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| SCHEMBL6751823 | 0.75 | TOP2A (0.63) | NISCHTOP2ATOP2BALDH1A1CYP1A2 | |
| SCHEMBL8141372 | 0.74 | NISCH (1.00) | NISCHTOP2ATOP2BALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | disclosed |
| WO-1996040997-A1 | METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-12-19 | — | — | WO | disclosed |