Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8537424 | 0.69 | — | — | |
| SCHEMBL8776108 | 0.69 | SLC6A4 (0.40) | SLC6A4SLC6A3 | |
| SCHEMBL8775944 | 0.68 | SLC6A4 (0.36) | SLC6A4SLC6A3 | |
| SCHEMBL8168093 | 0.66 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL8501697 | 0.65 | SLC6A4 (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL6469961 | 0.65 | CHRM3 (0.34) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6559900 | 0.64 | — | — | |
| SCHEMBL6739410 | 0.64 | EPHX2 (0.33) | — | |
| SCHEMBL7124697 | 0.63 | EPHX2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL5084215 | 0.60 | CNR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710224-A | CATALYTIC POLYMERIZATION OF ETHYLENE USING FLUORENE INDENYL ETHANE ZIRCONIUM DICHLORIDE WITH METALLOCENE | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0729978-A1 | Polyethylene and method for production thereof | PHILLIPS PETROLEUM COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |