Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.70 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544076 | 0.83 | TBXAS1 (1.00) | TBXAS1PTGDR2TBXA2R | |
| SCHEMBL9814980 | 0.76 | TBXAS1 (0.63) | TBXAS1PTGDR2TBXA2R | |
| SCHEMBL8537431 | 0.75 | TBXAS1 (0.58) | TBXAS1PTGDR2TBXA2R | |
| SCHEMBL8541183 | 0.75 | TBXAS1 (0.73) | TBXAS1PTGDR2TBXA2R | |
| SCHEMBL8539271 | 0.75 | TBXAS1 (0.79) | TBXAS1PTGDR2TBXA2R | |
| SCHEMBL19368676 | 0.74 | PTGDR2 (0.57) | PTGDR2 | |
| SCHEMBL8543306 | 0.74 | TBXAS1 (0.85) | TBXAS1PTGDR2TBXA2R | |
| SCHEMBL9814947 | 0.71 | TBXAS1 (0.56) | TBXAS1PTGDR2TBXA2R | |
| SCHEMBL13677413 | 0.71 | PTGDR2 (1.00) | PTGDR2TBXA2R | |
| SCHEMBL8539406 | 0.71 | TBXAS1 (0.70) | TBXAS1PTGDR2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |
| EP-0715627-A1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | Pfizer Limited (GB) | 1996-06-12 | — | — | EP | claimed |
| WO-1995006046-A1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LIMITED (GB) | 1995-03-02 | — | — | WO | claimed |