SCHEMBL8537629

SCHEMBL8537629

O=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.54
PPARA Q07869 3/20 0.54
PPARG P37231 2/20 0.54
FABP2 P12104 1/20 0.54
SLC22A12 Q96S37 1/20 0.54
SRD5A2 P31213 1/20 0.52
STS P08842 2/20 0.51
ELANE P08246 1/20 0.51
MAPK1 P28482 2/20 0.47
ENPP1 P22413 3/20 0.47
ENPP3 O14638 2/20 0.47
ENPP2 Q13822 2/20 0.47
ITGA1 P56199 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3668194 0.91 STS (0.60) PPARAPPARGFABP2SLC22A12SRD5A2
SCHEMBL2941459 0.88 CA2 (0.57) PPARAPPARGMAPK1ENPP1ENPP3
SCHEMBL8671149 0.87 HPGD (0.49) HPGDPPARAPPARGFABP2SLC22A12
SCHEMBL8690353 0.86 STS (0.67) SRD5A2STSELANEITGA1
SCHEMBL24095014 0.85 STS (0.53) HPGDSRD5A2STSELANEMAPK1
SCHEMBL9234669 0.85 STS (0.53) SRD5A2STSMAPK1ENPP1ENPP2
SCHEMBL8331932 0.83 LMNA (0.53) SRD5A2STSELANECA1CA2
SCHEMBL8533900 0.83 CA1 (0.46) PPARAPPARGFABP2SLC22A12STS
SCHEMBL7108334 0.83 CA1 (0.46) PPARAPPARGFABP2SLC22A12STS
SCHEMBL17287535 0.82 CA1 (0.52) PPARAPPARGENPP1ENPP3ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190844-B1 BAITS SCHERING AGROCHEMICALS LIMITED (GB) 1991-10-23 EP claimed
EP-0003913-B1 PESTICIDALLY ACTIVE BENZOPHENONE HYDRAZONE DERIVATIVES, METHODS FOR THEIR PRODUCTION AND PESTICIDAL COMPOSITIONS AND METHODS FBC LIMITED (GB) 1984-05-02 EP claimed
EP-0662472-B1 Hydrazone derivates as pesticides CIBA GEIGY AG (CH) 1998-03-11 EP disclosed
US-5563174-A LOW TOXICITY TO MAMMALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-08 US disclosed
US-5536748-A Hydrazone compound and insecticide containing the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-16 US disclosed
EP-0684229-A1 Sulfamide derivatives NIHON BAYER AGROCHEM K.K. (JP) 1995-11-29 EP disclosed
EP-0662472-A1 Hydrazone derivates as pesticides CIBA-GEIGY AG (CH) 1995-07-12 EP disclosed
EP-0647622-A1 Hydrazone compound and insecticide containing the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-12 EP disclosed
EP-0355832-B1 A HYDRAZONE COMPOUND AND PRODUCTION THEREFOR, AND AN INSECTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed
US-4980373-A Hydrazone compound and production therefor, and an insecticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-25 US disclosed
EP-0355832-A1 A hydrazone compound and production therefor, and an insecticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-02-28 EP disclosed