Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694410 | 0.89 | MEN1 (0.63) | SMN1; SMN2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL31707847 | 0.85 | KMT2A (0.59) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL31707846 | 0.85 | KMT2A (0.59) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| 4-Nitrophenyl Phenylcarbamate SCHEMBL1434931 | 0.84 | ALDH1A1 (0.62) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7547050 | 0.84 | CYP1A2 (0.69) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL882954 | 0.83 | TSHR (0.54) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3573967 | 0.82 | MAPT (0.66) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11981819 | 0.82 | CYP1A2 (0.59) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8533351 | 0.82 | MAPT (0.64) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL132757 | 0.82 | MEN1 (0.65) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |