Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539686 | 1.00 | ABCC9 (0.55) | ABCC9ABCB1 | |
| SCHEMBL8589788 | 0.88 | KDM4E (0.47) | ABCC9ABCB1 | |
| SCHEMBL8542268 | 0.87 | ABCC9 (0.55) | ABCC9ABCB1 | |
| SCHEMBL8544242 | 0.87 | ABCB1 (0.56) | ABCC9ABCB1 | |
| SCHEMBL8535237 | 0.85 | ABCC9 (0.42) | ABCC9ABCB1 | |
| Water SCHEMBL8539489 | 0.85 | ABCC9 (0.42) | ABCC9ABCB1 | |
| SCHEMBL8536420 | 0.85 | ABCC9 (0.42) | ABCC9ABCB1 | |
| SCHEMBL9472103 | 0.84 | ABCB1 (0.59) | ABCC9ABCB1 | |
| SCHEMBL8544061 | 0.81 | ABCB1 (0.40) | ABCC9ABCB1 | |
| SCHEMBL8539388 | 0.81 | ABCB1 (0.40) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489327-B1 | Chroman derivatives | MERCK PATENT GMBH (DE) | 1998-05-27 | — | — | EP | claimed |
| EP-0489327-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1992-06-10 | — | — | EP | claimed |
| JP-4300880-A | — | — | None | — | — | JP | disclosed |
| EP-0489327-B1 | Chroman derivatives | MERCK PATENT GMBH (DE) | 1998-05-27 | — | — | EP | disclosed |
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5238937-A | PYRIDAZINY OR OXODIHYDROPYRIDAZINYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| JP-H04300880-A | CHROMAN DERIVATIVE | MERCK PATENT GMBH | 1992-10-23 | — | — | JP | disclosed |
| EP-0489327-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1992-06-10 | — | — | EP | disclosed |