Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694340 | 0.89 | KDM4E (0.49) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9694170 | 0.86 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TSHRRAB9APOLB | |
| SCHEMBL4982157 | 0.81 | CHRM2 (0.61) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31088058 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4062858 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL24107663 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7256602 | 0.79 | P2RX7 (0.43) | ALDH1A1L3MBTL1TSHRMAPTP2RX7 | |
| SCHEMBL8534431 | 0.79 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TSHRMAPTP2RX7 | |
| SCHEMBL12204906 | 0.79 | P2RX7 (0.43) | ALDH1A1L3MBTL1TSHRMAPTP2RX7 | |
| SCHEMBL31277349 | 0.79 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1TSHRMAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |