Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621116 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31360425 | 0.95 | CRBN (0.32) | CRBNBRD4BRD2 | |
| SCHEMBL3512776 | 0.84 | — | — | |
| SCHEMBL8487154 | 0.73 | — | — | |
| Iodide SCHEMBL8540820 | 0.72 | PLA2G7 (0.33) | — | |
| SCHEMBL27030667 | 0.70 | PLA2G7 (0.36) | CRBNBRD4BRD2 | |
| SCHEMBL22070 | 0.70 | — | — | |
| SCHEMBL21859461 | 0.70 | MAPT (0.33) | — | |
| SCHEMBL18937480 | 0.70 | PIK3CD (0.33) | — | |
| SCHEMBL31319117 | 0.69 | ALDH1A1 (0.36) | CRBNBRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592676-B1 | IMINOSULFONYLUREA DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL IND LTD (JP) | 1998-09-30 | — | — | EP | disclosed |
| US-5686390-A | Iminosulfonylurea derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| US-5604179-A | PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| US-5500406-A | 1-AZOLYLIDENEIMINIOSULFONYL-3-PYRIMIDIN-2-YL UREAS; LOW DOSAGE; HIGH SELECTIVITY; CROPS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0592676-A1 | IMINOSULFONYLUREA DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1994-04-20 | — | — | EP | disclosed |