Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534588 | 0.85 | GPR119 (0.49) | GPR119MAPT | |
| SCHEMBL8532168 | 0.84 | GPR119 (0.53) | GPR119 | |
| SCHEMBL8537302 | 0.84 | GPR119 (0.48) | GPR119ACACBMAPT | |
| SCHEMBL15253294 | 0.83 | GPR119 (0.51) | GPR119MAPT | |
| SCHEMBL9267483 | 0.82 | GPR119 (0.56) | GPR119 | |
| SCHEMBL15252996 | 0.82 | GPR119 (0.63) | GPR119 | |
| SCHEMBL8537175 | 0.81 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL8536451 | 0.81 | CHRNA7 (0.48) | GPR119ACACB | |
| SCHEMBL8532077 | 0.81 | GPR119 (0.55) | GPR119 | |
| SCHEMBL8511477 | 0.80 | GPR119 (0.49) | GPR119ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |