Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538022 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1PKMKMT2ALMNA | |
| SCHEMBL8534662 | 0.86 | CCKBR (0.42) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8534655 | 0.86 | CCKBR (0.42) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8536814 | 0.86 | CCKBR (0.44) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8536809 | 0.86 | CCKBR (0.44) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7543596 | 0.85 | ALDH1A1 (0.44) | MEN1ALDH1A1PKMKMT2ALMNA | |
| SCHEMBL7543604 | 0.85 | ALDH1A1 (0.44) | MEN1ALDH1A1PKMKMT2ALMNA | |
| SCHEMBL8538016 | 0.84 | CCKBR (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8538017 | 0.84 | CCKBR (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8535348 | 0.84 | TP53 (0.42) | LMNAGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |