Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.48 |
| ▸ | ITGAV | P06756 | 17/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 9/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.42 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.42 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538619 | 0.94 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8542414 | 0.87 | PTGIR (0.39) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8542609 | 0.82 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8542565 | 0.81 | NPC1 (0.44) | — | |
| SCHEMBL8538630 | 0.79 | ITGB3 (0.51) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8541765 | 0.78 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7753126 | 0.77 | ADRA2A (0.58) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| Hydrochloric Acid SCHEMBL7562956 | 0.76 | ADRA2A (0.57) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8537926 | 0.76 | ITGB3 (0.50) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| Hydrochloric Acid SCHEMBL6224028 | 0.74 | ITGB3 (0.58) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |