Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | FABP7 | O15540 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446422 | 0.84 | MAPT (0.67) | MAPTTDP1RXRARXRBEPHX1 | |
| SCHEMBL12469524 | 0.81 | RXRA (0.51) | MAPTTDP1RXRARXRBEPHX1 | |
| SCHEMBL8540453 | 0.80 | MAPT (0.49) | MAPTTDP1FABP7FABP3FABP5 | |
| Trimethylammonium SCHEMBL27796894 | 0.80 | MAPT (0.61) | MAPTTDP1RXRARXRBEPHX1 | |
| SCHEMBL95954 | 0.79 | CA4 (0.48) | MAPTTDP1 | |
| SCHEMBL4260925 | 0.79 | EPHX1 (0.55) | MAPTTDP1RXRARXRBEPHX1 | |
| SCHEMBL29053641 | 0.79 | EPHX1 (0.55) | RXRARXRBEPHX1FABP7FABP3 | |
| SCHEMBL28032593 | 0.79 | LMNA (0.66) | MAPTTDP1RXRARXRB | |
| SCHEMBL30833342 | 0.78 | ELANE (0.55) | MAPTTDP1RXRARXRBEPHX1 | |
| SCHEMBL16820804 | 0.78 | ELANE (0.55) | MAPTTDP1RXRARXRBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |