Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
| ▸ | CDA | P32320 | 6/20 | 0.43 |
| ▸ | TK2 | O00142 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536800 | 1.00 | PYGM (0.46) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL8536802 | 1.00 | PYGM (0.46) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL2056570 | 0.99 | SLC28A1 (0.47) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL15689564 | 0.84 | PYGM (0.46) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL26970055 | 0.83 | PYGM (0.53) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL27804325 | 0.82 | SLC28A1 (0.46) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6753689 | 0.79 | TK2 (0.60) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL8333791 | 0.79 | TK2 (0.60) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL27773751 | 0.79 | TK2 (0.60) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6671442 | 0.78 | SLC28A1 (0.53) | PYGMSLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851866-A1 | THERAPEUTIC COMPOUNDS | Oxford GlycoSciences (UK) Limited (GB) | 1998-07-08 | — | — | EP | disclosed |
| WO-1997000882-A1 | THERAPEUTIC COMPOUNDS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 1997-01-09 | — | — | WO | disclosed |