Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545535 | 0.91 | HTT (0.45) | ALDH1A1HTTKDM4EAKR1C3L3MBTL1 | |
| SCHEMBL8544164 | 0.91 | TTPA (0.43) | ALDH1A1HTTKDM4EAKR1C3L3MBTL1 | |
| SCHEMBL9266621 | 0.84 | CYP3A4 (0.46) | ALDH1A1HTTAKR1C3L3MBTL1POLB | |
| SCHEMBL8542945 | 0.81 | TTPA (0.44) | ALDH1A1AKR1C3LMNAKMT2AMEN1 | |
| SCHEMBL8544229 | 0.81 | TTPA (0.44) | ALDH1A1AKR1C3LMNAKMT2AALOX15 | |
| SCHEMBL8543302 | 0.81 | TTPA (0.45) | KMT2AMEN1GAA | |
| SCHEMBL8543715 | 0.77 | PTGS1 (0.51) | ALDH1A1HTTAKR1C3L3MBTL1POLB | |
| SCHEMBL4322635 | 0.73 | GFER (0.42) | ALDH1A1HTTAKR1C3L3MBTL1LMNA | |
| SCHEMBL8540281 | 0.73 | TTPA (0.46) | KMT2AMEN1 | |
| SCHEMBL8539212 | 0.72 | CYP3A4 (0.47) | ALDH1A1KDM4EAKR1C3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587499-B1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR (FR) | 1998-04-29 | — | — | EP | disclosed |
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |