Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.89 |
| ▸ | PPARG | P37231 | 10/20 | 0.89 |
| ▸ | PPARD | Q03181 | 2/20 | 0.74 |
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422552 | 1.00 | PPARA (0.89) | PPARAPPARGPPARDACECYP1A2 | |
| SCHEMBL7331137 | 1.00 | PPARA (0.89) | PPARAPPARGPPARDACECYP1A2 | |
| SCHEMBL3362562 | 0.90 | PPARA (0.90) | PPARAPPARGPPARDACE | |
| SCHEMBL3582418 | 0.90 | PPARA (0.90) | PPARAPPARGPPARDACE | |
| SCHEMBL5853138 | 0.90 | PPARA (0.90) | PPARAPPARGPPARDACE | |
| SCHEMBL4966773 | 0.89 | PPARA (0.84) | PPARAPPARGPPARDACE | |
| SCHEMBL7314920 | 0.89 | PPARA (0.71) | PPARAPPARGPPARDACECYP1A2 | |
| Hydrochloric Acid SCHEMBL28347115 | 0.88 | PPARA (0.88) | PPARAPPARGPPARDACE | |
| Hydrochloric Acid SCHEMBL28347112 | 0.88 | PPARA (0.88) | PPARAPPARGPPARDACE | |
| SCHEMBL1278177 | 0.88 | PPARA (0.89) | PPARAPPARGPPARDACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589151-A | Diagnostic or therapeutic somatostatin or bombesin analog linkers and uses thereof | UNIV TULANE (US) | 2005-03-02 | — | — | CN | disclosed |
| US-5821329-A | Cyclic peptide inhibitors of β1 and β2 integrin-mediated adhesion | TANABE SEIYAKU CO., LTD. (JP) | 1998-10-13 | — | — | US | disclosed |
| WO-1996040781-A1 | CYCLIC PEPTIDE INHIBITORS OF β1 AND β2 INTEGRIN-MEDIATED ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-19 | — | — | WO | disclosed |