SCHEMBL4422552

SCHEMBL4422552

Cc1ccc(CSC[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1

nearest known ligand 0.89

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 12/20 0.89
PPARG P37231 10/20 0.89
PPARD Q03181 2/20 0.74
ACE P12821 2/20 0.61
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8538273 1.00 PPARA (0.89) PPARAPPARGPPARDACECYP1A2
SCHEMBL7331137 1.00 PPARA (0.89) PPARAPPARGPPARDACECYP1A2
SCHEMBL3362562 0.90 PPARA (0.90) PPARAPPARGPPARDACE
SCHEMBL3582418 0.90 PPARA (0.90) PPARAPPARGPPARDACE
SCHEMBL5853138 0.90 PPARA (0.90) PPARAPPARGPPARDACE
SCHEMBL4966773 0.89 PPARA (0.84) PPARAPPARGPPARDACE
SCHEMBL7314920 0.89 PPARA (0.71) PPARAPPARGPPARDACECYP1A2
Hydrochloric Acid SCHEMBL28347115 0.88 PPARA (0.88) PPARAPPARGPPARDACE
Hydrochloric Acid SCHEMBL28347112 0.88 PPARA (0.88) PPARAPPARGPPARDACE
SCHEMBL1278177 0.88 PPARA (0.89) PPARAPPARGPPARDACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612441-B2 Polypeptide and therapeutic uses thereof VITALIXIR (BEIJING) CO., LTD (CN) 2026-04-28 US disclosed
EP-3127914-B1 LONG-ACTING ADRENOMEDULLIN DERIVATIVES UNIV MIYAZAKI (JP) 2025-12-17 EP disclosed
CN-118679179-B Long-acting GLP-1 polypeptide compound, composition and application thereof 内蒙古博睿精创科技有限公司 2025-05-09 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
CN-113614102-B Novel polypeptides and therapeutic uses thereof 鸿绪生物医药科技(北京)有限公司 2024-08-13 CN disclosed
CN-118126124-A Bioactive polypeptide with QRRAD structure, composition and application thereof 深圳市肽金生物科技有限公司 2024-06-04 CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
CN-116650424-A Novel polypeptide formulations and therapeutic uses thereof 鸿绪生物医药科技(北京)有限公司 2023-08-29 CN disclosed
US-20230263896-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF VITALIXIR (BEIJING) CO., LTD (CN) 2023-08-24 US disclosed
US-4716147-A NATRIURETIC POLYPEPTIDES MONSANTO COMPANY (US) 1987-12-29 US disclosed
US-4684621-A OLIGOPEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1987-08-04 US disclosed
US-4684620-A Cyclic polypeptides having mu-receptor specificity GIBSON-STEPHENS NEUROPHARMACEUTICALS, INC. (US) 1987-08-04 US disclosed
US-4658015-A ANTAGONIST OF VASSOPRESSIN AND OXYTOCIN SMITHKLINE BECKMAN CORPORATION (US) 1987-04-14 US disclosed
EP-0192742-A1 CYCLIC POLYPEPTIDES HAVING MU-RECEPTOR SPECIFICITY GIBSON-STEPHENS NEUROPHARMACEUTICALS, INC. (US) 1986-09-03 EP disclosed
US-4604378-A CYCLIC POLYPEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1986-08-05 US disclosed
EP-0182627-A2 Basic V1-vasopressin antagonists SMITHKLINE BECKMAN CORPORATION (US) 1986-05-28 EP disclosed
WO-1986001516-A1 CYCLIC POLYPEPTIDES HAVING MU-RECEPTOR SPECIFICITY GIBSON-STEPHENS NEUROPHARMACEUTICALS, INC. (US) 1986-03-13 WO disclosed
US-4543349-A Basic heptapeptide vasopressin antagonists SMITHKLINE BECKMAN CORPORATION (US) 1985-09-24 US disclosed
US-4515920-A Synthesis of peptides and proteins THE ROCKEFELLER UNIVERSITY (US) 1985-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612441-B2 Polypeptide and therapeutic uses thereof VIP, GCG, GLS PPARA 3619/4885PPARG 1881/4885PPARD 4337/4885
US-20230263896-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF VIP, IAPP, LNPEP PPARA 2927/4885PPARG 3932/4885PPARD 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.