Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.51 |
| ▸ | BCL2 | P10415 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494756 | 0.97 | HIF1A (0.54) | HIF1ABCL2MCL1KAT6AMAPT | |
| SCHEMBL7742090 | 0.91 | HIF1A (0.56) | HIF1AMAPT | |
| SCHEMBL8543770 | 0.90 | HIF1A (0.51) | HIF1AMAPT | |
| SCHEMBL7493427 | 0.88 | HIF1A (0.43) | HIF1ABCL2MCL1KAT6AMAPT | |
| SCHEMBL7501613 | 0.88 | HIF1A (0.54) | HIF1AKAT6A | |
| SCHEMBL7500390 | 0.86 | HIF1A (0.54) | HIF1AMAPT | |
| SCHEMBL7502688 | 0.83 | HIF1A (0.55) | HIF1AKAT6A | |
| SCHEMBL7501818 | 0.82 | HIF1A (0.45) | HIF1AMAPT | |
| SCHEMBL7498106 | 0.81 | HIF1A (0.51) | HIF1APTGS2 | |
| SCHEMBL7545129 | 0.79 | HIF1A (0.43) | HIF1AKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |