Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495296 | 0.86 | AKR1B1 (0.48) | HSD17B10GABRA5GABRB2NPSR1KDM4E | |
| SCHEMBL22070781 | 0.79 | AKR1B1 (0.41) | HSD17B10GABRA5GABRB2NPSR1KDM4E | |
| SCHEMBL2310375 | 0.78 | KDM4E (0.57) | KDM4ETDP1LMNA | |
| SCHEMBL27860588 | 0.77 | AKR1B1 (0.44) | HSD17B10GABRA5GABRB2NPSR1KDM4E | |
| SCHEMBL2731062 | 0.77 | GABRA5 (0.47) | HSD17B10GABRA5GABRB2KDM4ESMN1; SMN2 | |
| SCHEMBL29781523 | 0.77 | GABRA5 (0.47) | HSD17B10GABRA5GABRB2KDM4ESMN1; SMN2 | |
| SCHEMBL29755971 | 0.76 | P2RX7 (0.50) | KDM4ESMN1; SMN2CYP2C19 | |
| SCHEMBL868879 | 0.76 | P2RX7 (0.50) | KDM4ESMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL5471608 | 0.76 | GABRA5 (0.46) | HSD17B10GABRA5GABRB2KDM4ESMN1; SMN2 | |
| SCHEMBL18549597 | 0.74 | PDE5A (0.47) | HSD17B10GABRA5GABRB2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069573-A1 | PROCESS FOR SEPARATING AMERICIUM FROM OTHER METALLIC ELEMENTS PRESENT IN AN ACIDIC AQUEOUS OR ORGANIC PHASE AND APPLICATIONS THEREOF | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2012-05-31 | — | — | WO | disclosed |