SCHEMBL8538532

SCHEMBL8538532

CCCCCOC(=O)[CH]CC(=O)OCCCCC

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.57
HCAR2 Q8TDS4 3/20 0.55
ATM Q13315 1/20 0.53
TSHR P16473 3/20 0.50
HPGD P15428 1/20 0.50
RAD52 P43351 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
FAAH O00519 2/20 0.47
DGKA P23743 1/20 0.47
HTR2C P28335 1/20 0.46
EPHX1 P07099 1/20 0.44
ALDH1A1 P00352 1/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9165492 0.98 NAAA (0.60) NAAAHCAR2ATMTSHRHPGD
SCHEMBL11574796 0.96 NAAA (0.58) NAAAHCAR2ATMTSHRHPGD
SCHEMBL11571102 0.94 ATM (0.61) NAAAHCAR2ATMTSHRHPGD
SCHEMBL6637984 0.89 NAAA (0.46) NAAAHCAR2ATMTSHRHPGD
SCHEMBL8517576 0.87 TSHR (0.57) NAAAHCAR2ATMTSHRHPGD
SCHEMBL8516916 0.87 TSHR (0.53) NAAAHCAR2ATMTSHRHPGD
SCHEMBL11500627 0.86 HCAR2 (0.50) NAAAHCAR2ATMTSHRHPGD
SCHEMBL4910652 0.84 NAAA (0.61) NAAAHCAR2ATMTSHRHPGD
SCHEMBL10714622 0.82 NAAA (0.64) NAAAHCAR2ATMTSHRRAD52
SCHEMBL7627118 0.82 NAAA (0.64) NAAAHCAR2ATMTSHRRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661310-B1 Cyclo-olefincopolymers and process for their preparation TICONA GMBH (DE) 1999-07-21 EP disclosed
EP-0661308-B1 Cyclo-olefin copolymers and process for their preparation TICONA GMBH (DE) 1999-06-02 EP disclosed
US-5756623-A MOLDING MATERIALS FOR COMPRESSION MOLDING HOECHST AG (DE) 1998-05-26 US disclosed
EP-0661310-A2 Cyclo-olefincopolymers and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed
EP-0661308-A2 Cyclo-olefin copolymers and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed