Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517576 | 0.94 | TSHR (0.57) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL8538532 | 0.87 | NAAA (0.57) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL9165492 | 0.85 | NAAA (0.60) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL11574796 | 0.83 | NAAA (0.58) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL793169 | 0.81 | NAAA (0.59) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL11571102 | 0.81 | ATM (0.61) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL8541464 | 0.81 | TSHR (0.44) | TSHRHPGDNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL10835780 | 0.80 | HCAR2 (0.66) | TSHRNAAAHPGDHCAR2NPSR1 | |
| SCHEMBL8517577 | 0.80 | TSHR (0.74) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL28653942 | 0.80 | TSHR (0.64) | TSHRNAAAHPGDHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661310-B1 | Cyclo-olefincopolymers and process for their preparation | TICONA GMBH (DE) | 1999-07-21 | — | — | EP | disclosed |
| EP-0661308-B1 | Cyclo-olefin copolymers and process for their preparation | TICONA GMBH (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0661310-A2 | Cyclo-olefincopolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0661308-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |