Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029020 | 0.92 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8540447 | 0.83 | TACR1 (0.42) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8539280 | 0.82 | TACR1 (0.42) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8541413 | 0.81 | POLB (0.46) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8531284 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL7490694 | 0.74 | LMNA (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6998524 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8539528 | 0.72 | KMT2A (0.50) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL21467805 | 0.70 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL13678690 | 0.69 | MEN1 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720609-B1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LTD (GB) | 1998-11-11 | — | — | EP | disclosed |
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |