Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | RHOC | P08134 | 1/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542585 | 0.91 | RXFP1 (0.40) | RXFP1P2RX1GPR35LMNARHOC | |
| SCHEMBL8538607 | 0.88 | RXFP1 (0.39) | RXFP1P2RX1CYP1A2LMNA | |
| SCHEMBL8539103 | 0.80 | RXFP1 (0.41) | RXFP1LMNAPTGS1 | |
| SCHEMBL8538381 | 0.75 | PARP1 (0.38) | RXFP1 | |
| SCHEMBL8538801 | 0.75 | KDR (0.37) | RXFP1LMNA | |
| SCHEMBL8542380 | 0.73 | PARP1 (0.37) | RXFP1LMNA | |
| SCHEMBL8540539 | 0.72 | PARP1 (0.41) | — | |
| SCHEMBL6376058 | 0.72 | P2RY14 (0.50) | P2RX1TACR1GPR35LMNA | |
| SCHEMBL8536782 | 0.69 | NPC1 (0.37) | LMNA | |
| SCHEMBL8701052 | 0.69 | RXFP1 (0.42) | RXFP1P2RX1TACR1ACP1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |