Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538801 | 0.88 | KDR (0.37) | PARP1PARP10PARP15KDRPARP14 | |
| SCHEMBL8542380 | 0.86 | PARP1 (0.37) | PARP1PARP10PARP15KDRPARP14 | |
| SCHEMBL8538559 | 0.85 | PARP1 (0.38) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL8539103 | 0.85 | RXFP1 (0.41) | PARP1PARP10PARP15KDRPARP14 | |
| SCHEMBL8540539 | 0.85 | PARP1 (0.41) | PARP1PARP10PARP15KDRPARP14 | |
| SCHEMBL8536782 | 0.82 | NPC1 (0.37) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL8544132 | 0.82 | LMNA (0.39) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL8542355 | 0.81 | MAPT (0.42) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8542521 | 0.78 | CBS (0.37) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL8538586 | 0.75 | RXFP1 (0.43) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |