Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.35 |
| ▸ | ITGAV | P06756 | 4/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538381 | 0.85 | PARP1 (0.38) | PARP1PARP10PARP15PARP14KDR | |
| SCHEMBL8538801 | 0.85 | KDR (0.37) | PARP1PARP10PARP15PARP14KDR | |
| SCHEMBL8542380 | 0.83 | PARP1 (0.37) | PARP1PARP10PARP15PARP14KDR | |
| SCHEMBL8539103 | 0.82 | RXFP1 (0.41) | PARP1PARP10PARP15PARP14PKM | |
| SCHEMBL8536782 | 0.80 | NPC1 (0.37) | PARP1PARP10PARP15PARP14PKM | |
| SCHEMBL8538559 | 0.79 | PARP1 (0.38) | PARP1PARP10PARP15PARP14CREBBP | |
| SCHEMBL8542521 | 0.77 | CBS (0.37) | PARP1PARP10PARP15PARP14ALDH1A1 | |
| SCHEMBL8544132 | 0.77 | LMNA (0.39) | PARP1PARP10PARP15PARP14ALDH1A1 | |
| SCHEMBL8542355 | 0.77 | MAPT (0.42) | ALDH1A1MAPT | |
| SCHEMBL8441146 | 0.74 | PKM (0.48) | PARP1PARP10PARP15PARP14PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |