Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607767 | 0.77 | GAA (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5607683 | 0.76 | THRB (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7497385 | 0.71 | SENP1 (0.53) | SIRT2RHOAROCK1 | |
| SCHEMBL7497378 | 0.71 | SENP1 (0.53) | SIRT2RHOAROCK1 | |
| SCHEMBL15490435 | 0.67 | ABL1 (0.65) | ABL1SRCSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL19426791 | 0.67 | KDR (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL31610174 | 0.67 | HPGD (0.58) | ABL1SRCSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8352521 | 0.66 | ABL1 (0.58) | ABL1SRCEGFRBCRROCK1 | |
| SCHEMBL29836794 | 0.65 | BCHE (0.48) | ALDH1A1MAPTLMNANPC1ROCK1 | |
| SCHEMBL19476377 | 0.65 | NPC1 (0.59) | ABL1SRCEGFRAURKANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |