Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055741 | 0.88 | TSHR (0.43) | TSHRTDP1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL7980205 | 0.86 | TSHR (0.44) | TSHRTDP1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL319564 | 0.85 | TSHR (0.30) | TSHRTDP1 | |
| SCHEMBL706741 | 0.85 | ADRB2 (0.41) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL704492 | 0.82 | ADRB2 (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL706738 | 0.82 | ADRB2 (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL704381 | 0.82 | ADRB2 (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL706468 | 0.82 | ADRB2 (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL11332079 | 0.78 | TSHR (0.40) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL5575092 | 0.78 | TSHR (0.40) | TSHRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770754-A | Method of preparing polysulphidic silyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-23 | — | — | US | disclosed |