SCHEMBL7980205

SCHEMBL7980205

CCCCO[SiH](CCCCCl)OCCCC

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31055741 0.93 TSHR (0.43) TSHRALDH1A1TDP1ADRB2ADRB1
SCHEMBL600890 0.89 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL704381 0.89 ADRB2 (0.39) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL8538739 0.86 TSHR (0.39) TSHRALDH1A1TDP1ADRB2ADRB1
SCHEMBL5572088 0.84 TSHR (0.40) TSHRADRB2ADRB1ADRB3
SCHEMBL11332079 0.84 TSHR (0.40) TSHRADRB2ADRB1ADRB3
SCHEMBL5575092 0.84 TSHR (0.40) TSHRADRB2ADRB1ADRB3
SCHEMBL706468 0.84 ADRB2 (0.39) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL706738 0.84 ADRB2 (0.39) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL320003 0.82 TSHR (0.39) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3260515-A1 POLISHING COMPOSITION Fujimi Incorporated (JP) 2017-12-27 EP disclosed
US-20160288289-A1 POLISHING COMPOSITION FUJIMI INCORPORATED (JP) 2016-10-06 US disclosed
EP-3048152-A1 POLISHING COMPOSITION Fujimi Incorporated (JP) 2016-07-27 EP disclosed
US-6277902-B1 RUBBER COMPOUNDS COMPRISING SOLUBLE RUBBER, HYDROPHOBIZED FILLER HAVING SPECIFIED METHANOL WETTABILITY, SUPPORTEDPOLYSULFIDIC-SILANE COMPOUNDS PREPARED BY REACTION OF HALOALKYLSILANES, ORGANIC HALOGEN COMPOUNDS AND POLYSULFIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
US-5770754-A Method of preparing polysulphidic silyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1998-06-23 US disclosed