Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950808 | 0.84 | LMNA (0.42) | TSHRMDM4TP53MDM2CETP | |
| SCHEMBL27135634 | 0.77 | TSHR (0.50) | TSHRKDM4EPOLBHSP90AA1HSP90AB1 | |
| SCHEMBL943046 | 0.76 | TSHR (0.57) | TSHRKDM4EPKMPOLBCETP | |
| SCHEMBL6953465 | 0.75 | TSHR (0.49) | TSHRKDM4EPKMPOLBPPARA | |
| SCHEMBL10028917 | 0.74 | TSHR (0.55) | TSHRKDM4E | |
| SCHEMBL20738184 | 0.74 | TSHR (0.55) | TSHRKDM4E | |
| SCHEMBL20863067 | 0.73 | TSHR (0.53) | TSHRKDM4EPKMPOLB | |
| SCHEMBL8538646 | 0.73 | ACHE (0.50) | POLBMDM4TP53MDM2CETP | |
| SCHEMBL19705414 | 0.73 | TSHR (0.53) | TSHRKDM4ECYSLTR2CYSLTR1 | |
| SCHEMBL7367444 | 0.72 | TSHR (0.45) | TSHRKDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |