Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541862 | 0.92 | POLB (0.66) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL8542093 | 0.88 | POLB (0.64) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL8540059 | 0.86 | POLB (0.69) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL8540505 | 0.85 | POLB (0.68) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL18435561 | 0.85 | POLB (0.71) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL8904149 | 0.84 | HDAC6 (0.55) | FAAHPOLBGRIN2BHDAC3HDAC4 | |
| SCHEMBL8540623 | 0.82 | POLB (0.71) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL24043594 | 0.81 | POLB (0.69) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL16591625 | 0.81 | POLB (0.69) | FAAHPOLBGRIN2BNPC1TDP1 | |
| SCHEMBL5369484 | 0.81 | POLB (0.69) | FAAHPOLBGRIN2BNPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |