Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654223 | 0.84 | NISCH (0.50) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL5248703 | 0.83 | CSNK1A1 (0.44) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL32667989 | 0.81 | CSNK1A1 (0.42) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL8537911 | 0.81 | AMY1A (0.45) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL15651168 | 0.80 | NISCH (0.46) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL8536469 | 0.80 | CSNK1A1 (0.41) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL8541165 | 0.79 | NISCH (0.53) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL1045307 | 0.79 | NISCH (0.44) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL4063139 | 0.79 | ALDH1A1 (0.41) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL31332460 | 0.79 | CSNK1A1 (0.41) | CSNK1A1TYRO3DYRK1BNISCHMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |