Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416131 | 0.91 | HTR1A (0.79) | HTR1A | |
| Hydrochloric Acid SCHEMBL4426960 | 0.90 | HTR1A (0.77) | HTR1A | |
| SCHEMBL9696723 | 0.90 | HTR1A (0.67) | HTR1A | |
| SCHEMBL7530566 | 0.89 | HTR1A (0.76) | HTR1A | |
| Hydrochloric Acid SCHEMBL7954846 | 0.89 | HTR1A (0.75) | HTR1A | |
| SCHEMBL7956463 | 0.88 | HTR1A (0.77) | HTR1A | |
| SCHEMBL9696788 | 0.87 | HTR1A (0.79) | HTR1A | |
| SCHEMBL8544143 | 0.87 | HTR1A (0.73) | HTR1A | |
| SCHEMBL17242081 | 0.87 | HTR1A (0.61) | HTR1A | |
| SCHEMBL17242348 | 0.87 | HTR1A (0.61) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496222-B1 | Indole derivatives | MERCK PATENT GMBH (DE) | 1998-09-09 | — | — | EP | disclosed |
| EP-0496222-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |