Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539208 | 0.94 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8537705 | 0.92 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL8544626 | 0.88 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9414205 | 0.87 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9036191 | 0.86 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL8539663 | 0.86 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8539427 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8543557 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8541171 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9037160 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442473-B1 | Pyrimidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-08-19 | — | — | EP | claimed |
| US-5162326-A | Antagonists for angeotensin; hypotensive agents; treatment for heart diseases, strokes | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | claimed |
| EP-0442473-A1 | Pyrimidinedione derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-21 | — | — | EP | claimed |