Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539427 | 0.91 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8537705 | 0.90 | AGTR1 (0.43) | AGTR1AGTR2PPARG | |
| SCHEMBL8541171 | 0.90 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL8539208 | 0.89 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9414237 | 0.88 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL8539677 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9532741 | 0.84 | PPARG (0.43) | AGTR1AGTR2PPARG | |
| SCHEMBL8884970 | 0.84 | PPARG (0.43) | PPARG | |
| SCHEMBL9414259 | 0.82 | HPGD (0.35) | PPARG | |
| SCHEMBL9037151 | 0.81 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442473-B1 | Pyrimidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5162326-A | Antagonists for angeotensin; hypotensive agents; treatment for heart diseases, strokes | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0442473-A1 | Pyrimidinedione derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-21 | — | — | EP | disclosed |