Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420351 | 0.82 | TACR1 (0.42) | SLC6A4SLC6A2SLC6A3MAPTALDH1A1 | |
| SCHEMBL8546489 | 0.81 | CHRNA7 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8541939 | 0.81 | CHRNA7 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8541943 | 0.81 | CHRNA7 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8967406 | 0.81 | CHRNA7 (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8900770 | 0.78 | MEN1 (0.44) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8544813 | 0.72 | DRD1 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8544809 | 0.72 | DRD1 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8544812 | 0.72 | DRD1 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| Fumaric Acid SCHEMBL8545846 | 0.72 | MEN1 (0.41) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690842-B1 | 4-ARYLISOINDOLE ANALGESICS | ORTHO PHARMA CORP (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5508424-A | REDUCED SIDE EFFECTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |