Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674006 | 1.00 | STAT3 (0.45) | STAT3HTTMAOBMEN1HSP90AA1 | |
| SCHEMBL10772266 | 0.89 | STAT3 (0.46) | STAT3HTTMAOBMEN1KMT2A | |
| SCHEMBL4672032 | 0.84 | STAT3 (0.62) | STAT3HTTMEN1KMT2ATSHR | |
| SCHEMBL9096244 | 0.84 | STAT3 (0.62) | STAT3HTTMEN1KMT2ATSHR | |
| SCHEMBL8539874 | 0.84 | STAT3 (0.62) | STAT3HTTMEN1KMT2ATSHR | |
| SCHEMBL7997863 | 0.82 | STAT3 (0.54) | STAT3HTTKMT2ATSHRCASP1 | |
| SCHEMBL8744098 | 0.82 | STAT3 (0.54) | STAT3HTTKMT2ATSHRCASP1 | |
| SCHEMBL13483600 | 0.80 | STAT3 (0.52) | STAT3HTTTSHRCASP1MAPK1 | |
| SCHEMBL13483601 | 0.77 | STAT3 (0.48) | STAT3HTTMEN1KMT2ATSHR | |
| SCHEMBL9046232 | 0.77 | STAT3 (0.49) | STAT3HTTMAOBMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |