Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.64 |
| ▸ | ALB | P02768 | 4/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918 | 0.92 | BRD4 (0.57) | BCHEALBACHE | |
| SCHEMBL13345818 | 0.82 | BRD4 (0.51) | BCHEALBACHE | |
| SCHEMBL1003026 | 0.81 | MCHR1 (0.52) | BCHEALBACHE | |
| SCHEMBL1146660 | 0.78 | HTR2A (0.51) | — | |
| SCHEMBL7428637 | 0.78 | HTR2A (0.51) | — | |
| SCHEMBL30223533 | 0.78 | HTR2A (0.51) | — | |
| SCHEMBL7294032 | 0.78 | BCHE (0.49) | BCHEALBACHE | |
| SCHEMBL625913 | 0.75 | HTR6 (0.61) | BCHEALBACHE | |
| SCHEMBL984 | 0.74 | HTR2A (0.54) | — | |
| SCHEMBL3558226 | 0.73 | PTPN1 (0.54) | BCHEALBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360800-A | Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives | GLAXO GROUP LIMITED (GB) | 1994-11-01 | — | — | US | disclosed |
| EP-0306323-A2 | Lactam derivatives | GLAXO GROUP LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |